Top 5 Vertical Ergonomic Mouse

Let’s face it, computer mice are terrible for our posture. If you’re spending hours in front of a computer and have wrist/shoulder pain, consider getting a vertical ergonomic mouse, it’ll help relieve the pain. We’ve been using vertical ergonomic mice for years and from our experience, they actually work! 

If you suffer from wrist and shoulder pains, a vertical mouse may be what you need. We tested dozens of vertical ergonomic mice over the last few months, and out of the 12+ mice we’ve tested, here are our the Top 5 Vertical Ergonomic Mouse!   

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Top 5 Vertical Ergonomic Mouse

#5 DELUX Rechargeable Wireless Ergonomic Mouse

Delux M618DB Ergo Vertical Mouse Review



Decent hand angle

Smooth finish

Budget-friendly price

Lack of Mac customization support

Multiple ways to connect


Built-in battery


The DELUX Ergonomic Mouse is a budget-friendly option for those seeking a vertical ergonomic mouse. Its design resembles the Logitech MX Vertical, and it offers a hand angle of approximately 57 degrees for enhanced wrist comfort. However, its smooth texture may compromise grip stability, necessitating frequent adjustments during use.

In terms of functionality, the mouse features four buttons and a scroll wheel, but native compatibility for Mac systems requires third-party software. The placement of the thumb buttons below the thumb deviates from convention, potentially impacting user experience. While the silent click buttons minimize operational noise, the scroll wheel lacks tactile feedback and speed sensitivity, hindering rapid page navigation.

The mouse’s 500mAh internal battery offers extended usage duration and efficient recharging, but the dongle’s loose placement compromises accessibility. Despite these drawbacks, the optical sensor performs well on various surfaces except glass, and its wireless connectivity options cater to diverse user preferences.

In conclusion, the DELUX Ergonomic Mouse balances performance and affordability, making it a viable choice for budget-conscious consumers. 

Get yours on Amazon!

#4 ProtoArc EM11 Mouse



Sleek and futuristic design

Unconventional shape

Multiple ways to connect

Lack of Mac customization support

Silent buttons

Non speed sensitive scroll wheel

Built-in battery


The ProtoArc EM11 Mouse stands out with its sleek, futuristic design, featuring LED lights and a soft rubber coating that enhances grip and comfort. Its unconventional shape, may catch some off guard, particularly when readjusting the pointer, as the unique design introduces a slight rocking motion. Despite this, the EM11 offers practical features such as three DPI settings and silent main buttons, providing a smooth and responsive experience.

However, while the mouse excels in functionality, some drawbacks exist. While useful, the orange thumb buttons are not compatible with Mac systems without third-party software, potentially limiting its appeal to specific users. Additionally, the scroll wheel, while functional, may not match the precision of more advanced models, particularly for those accustomed to smarter scroll wheels.

On the upside, the built-in battery ensures months of usage before recharging, adding to the mouse’s convenience. Furthermore, its ability to connect wirelessly to multiple devices without a dongle is a welcome feature. However, the absence of USB-C connectivity for wired use may be a drawback for some.

The ProtoArc EM11 Mouse balances style and functionality, offering a visually captivating addition to any workspace at a competitive price. While it may not boast all the advanced features of pricier models, its distinctive design and reliable performance make it a compelling choice for those seeking a budget-friendly vertical mouse option.

Get your own ProtoArc mouse on Amazon!

#3 Kensington Vertical Ergonomic Mouse/Pro



Nice handling angle

Slightly shallower ergonomic angle

C-shape design 

Glossy buttons on the white variant

Small lip for the pinky 

Lack of Mac customization support

Wide range of DPI settings

Audible clicks

Affordable price


Kensington Vertical Wireless Mouse ReviewAmong the mice we’ve tested, the Kensington Vertical Ergonomic Mouse (and Pro Fit Ergo) shines as a top contender for those seeking budget friendly comfort and functionality. Both products had the same score BUT each product has its own pros and cons.

Both mice feature a 47-degree ergonomic angle may be slightly shallower than average vertical mice, but it offers stability and an easy transition from a normal mice.

One of the stand out handling features is the hand position. Traditional mice that position your hand in a V-shape, Kensington’s design adopts a more natural C-shape, ensuring a secure grip and effortless readjustment.

A notable feature of the Kensington Ergonomic Mouse is the small lip for your pinky, which prevents it from dragging and ensures smoother movements. On the Kensington Vertical Ergonomic Mouse, the DPI settings range from  800 to 2400, while the Kensington Pro Fit Ergo has a DPI range of 800-1600 (why isn’t it the other way?). The last thing to note is that the sensor on the normal version of the mouse works on glass surfaces while the Pro Fit Ergo does not.

Kensington Pro Fit Ergo Vertical Wireless Mouse Review

Both Kensington variants boast a sleek design, with the main body featuring a soft rubber coating for added comfort during prolonged use. However, while the darker variant sports a matte finish on the buttons, the white version’s glossy buttons feel greasy.

Unfortunately, Kensington’s software support falls short of expectations. While available for the Pro version, it fails to recognize the recognize the thumb buttons on Mac OS.  Additionally, the audible clicks of the buttons may prove distracting in quieter environments. The one upside of Kensington’s software is that you can customize the scroll wheel on the Pro Fit Ergo to recognize the speed at which you’re using the scroll wheel.

The Kensington Vertical Ergonomic Mouse, presents an excellent value proposition. It combines ergonomic design, sensitivity, and affordability. Despite some shortcomings in software support and button noise, it remains a top contender for those seeking a reliable and comfortable mouse for everyday use.

The Kensington Pro Fit Ergo is going to cost you $15 dollars but offers a bit more functionality through Kensington’s software.

Get the regular Kensington Vertical Ergonomic mouse on Amazon.

Get the Kensington Pro Fit Ergon on Amazon

#2 Logitech Life Vertical Ergonomic Mouse

Logitech Lift Vertical Ergonomic Mouse Review



Compact size


Nice handling angle

Won’t work on glass surface

Silent buttons


Built-in customization options


Multiple ways to connect


Speed-sensitive scroll wheel


We were initially skeptical of the Logitech Life Vertical Ergonomic mouse due to its small size. However, we were pleasantly surprised after actually using the product. But is it that great for  $75?

 Well, with Logitech, you’re not just paying for the physical product but investing in the accompanying hardware and software ecosystem. In a market where compatibility can be a headache, Logitech’s dedication to making its accessories work seamlessly across different platforms shines through. The ability to customize buttons for Mac applications through Logi+ Options is a game-changer, especially considering the frustrating experience with other vertical mice.

The mouse’s design features a 57-degree lift angle, a soft rubber-coated, textured palm area, making it comfortable to use for extended periods. Logitech states this mouse is made for people with small/medium hands. The thoughtful addition of silent click buttons ensures a distraction-free environment, and the speed scroll wheel adapts to your scrolling speed.Logitech Lift Vertical Ergonomic Mouse Buttons

Functionality-wise, the mouse doesn’t disappoint, either. It’s powered by a single AA battery, with the convenience of Bluetooth connectivity for up to three devices alongside the traditional dongle option. Plus, the magnetic bottom cover makes battery replacement/dongle access a breeze.

While the sensor may struggle on glass surfaces, its sensitivity settings are highly customizable. Its DPI range of 800 to 4000 which surpasses the industry average. The average mouse will have set DPI settings but Logitech allows you to customize the sensitivity of the mouse by increments of a 100 DPI.

Despite our initial skepticism, the Logitech Life Vertical Ergonomic mouse is worth $75. With its blend of ergonomic design, seamless compatibility, and advanced functionality, it’s a reliable companion for anyone needing a versatile and efficient pointing device.

See if Amazon has the Logitech Lift Vertical Mouse on sale!

#1 Logitech MX Vertical




Nice ergonomic design

Lack of storage for Unifying Receiver

Multiple ways to connect the mouse

Won’t work on glass surface

Built-in customization options


Nice grip and finish


The Logitech MX Vertical Advanced stands out among all the vertical ergonomic mice we’ve tested. Its ergonomic design, customizable features, and seamless connectivity options make it a top choice for those seeking comfort and functionality.

Its 57-degree vertical angle is slightly higher than average, which is suitable for reducing wrist strain. Additionally, its larger size caters to medium to larger hands.Logitech Lift Vertical Ergonomic Mouse Angle Position

The soft rubber coating provides durability and facilitates easy adjustments without compromising control. The array of buttons, including those for remapping, adds versatility, particularly for different applications, enhancing user experience. Especially for Mac OS users.

The Logitech MX Vertical has a lot of ways to connect. Whether wirelessly connecting to three devices via Bluetooth, using a Logitech Unifying Receiver, or opting for a wired connection, the MX Vertical offers flexibility to suit various preferences and setups.

However, there is a lack of storage for the Unifying Receiver and the sensor’s limitation on glass surfaces. The price tag may also deter some potential buyers, although the product’s quality justifies the cost.

Despite its minor drawbacks and premium price, the Logitech MX Vertical is a top contender. It offers a winning combination of comfort, customization, and connectivity.

Get your own Logitech MX Vertical Advanced here!

Best Ergonomic Mouse for Wrist Pain

When it comes to our product testing, we rank products on a multitude of criteria. For vertical ergonomic mice, approx. 35% of the score revolves around the comfort/wrist relief the mouse might provide. 

If your primary concern is alleviating wrist pain and you’re less focused on performance, Evoluent’s ergonomic mice might be your saving grace. For this round up, we tested two mice from Evoluent, the Vertical Mouse D and the Vertical Mouse 4.

With Evoluent’s mice, their design boasts a nearly 90-degree hand angle, significantly reducing forearm twisting. In fact, the next highest angle is around 60-degrees. Evoluent’s mice are also significantly larger than the average vertical mouse and are quite literal handful’s.  Having tested both the Vertical Mouse 4 and the Vertical Mouse D, we can confidently say that the Mouse D reigns supreme but here’s a breakdown of the two mice.

Evoluent vertical mouse D

The Evoluent Vertical Mouse D is a premium vertical ergonomic mouse that stands out among its competitors. It commands attention for its ergonomic design and its hefty price tag, making it the most expensive option in our test of 13 ergonomic mice. 

While the Evoluent Vertical Mouse D boasts several unique features, such as grooved buttons, a hand angle close to 90 degrees, and an additional DPI level compared to the average vertical mouse, these features fail to fully justify its exorbitant cost. In fact, despite Evoluent’s pride in their grooved buttons, they didn’t seem to make a significant difference during testing.

One notable aspect of the Evoluent Vertical Mouse D is its substantial size. This size, coupled with its unique button layout and the pinky lip at the bottom, aims to provide comfort and prevent hand fatigue during prolonged use. However, the glossy finish makes it look greasy and contributes to a slippery feel, while the noisy buttons can be distracting during use.

On the positive side, the Evoluent Vertical Mouse D offers the largest pronation angle among its competitors, ensuring minimal twisting of the forearm. The pinky lip does offer some relief from hand fatigue. Nevertheless, these pros are outweighed by the cons, particularly for users who frequently lift their mouse or require customization options. The lack of software for Mac users limits button functionality.

Ultimately, despite its ergonomic benefits, the Evoluent Vertical Mouse D falls short of the top five choices due to its size and usability issues.

See how much it’ll cost on Amazon!

Evoluent vertical mouse 4

Evoluent VerticalMouse 4 Review

The Evoluent Vertical Mouse 4 has many advantages, including its near-90-degree hand angle, bold design, and premium price tag. However, its performance fails to meet expectations.

On the positive side, the mouse’s pronounced pronation angle offers potential respite for users battling wrist strain. Additionally, its unconventional button layout, featuring extra thumb buttons, may enhance functionality for specific users seeking increased control and efficiency.

However, the Evoluent Vertical Mouse 4 has several significant drawbacks that detract from its overall appeal. Its hefty price makes it a hard sell when more affordable mice are out there. Moreover, the absence of customizable software for Mac users limits the utility of its additional buttons.

The size of the mouse is also a problem. The mouse is just too big, making it annoying for everyday use. Maneuverability is hindered, particularly for users accustomed to frequent mouse lifting, and the glossy finish adds a tactile discomfort. Additionally, the ergonomic lip designed to support the pinky often triggers unintended button clicks, introducing an unexpected inconvenience.

The Evoluent Vertical Mouse 4 may offer notable ergonomic advantages; however, its drawbacks are too big to ignore. Individuals seeking ergonomic relief without sacrificing usability may find better-suited alternatives elsewhere.

Only get this mouse if you can get a great deal. Check out the prices on Amazon.

Other Vertical Ergonomic Mice We’ve Tested

Anker Wireless Vertical Ergonomic Mouse

Anker Wireless Vertical Ergonomic Mouse ReviewAnker excels in charging accessories, but their venture into mouse-making falls short. Instead of crafting their own design, they opt for a pre-existing shell, indicating a lack of originality.

The Anker Wireless Vertical Ergonomic Mouse features three DPI levels and a silent scroll wheel, which initially seems promising. However, the oversized DPI button and inconveniently placed thumb buttons reveal design flaws.

Moreover, the mouse’s shape resembles a pinching rather than a cup-holding grip, which leads to discomfort during extended use. Despite its lightweight build, the cheap-feeling soft rubber coating detracts from its appeal.

While affordable, this mouse fails to justify its purchase. For a slightly higher price, superior ergonomic options are available elsewhere. We advise against choosing this Anker mouse; its flaws outweigh its benefits.

Lekvey Ergonomic Mouse

Lekvey Ergonomic Mouse has some unique features, like its angled design, but it’s not something worth going hype about.

Comfort-wise, it falls short. Its slim profile might not suit everyone, leading to an awkward grip compared to more traditional ergonomic mice. The rubber coating is supposed to improve grip but is not very effective. The mouse tends to slip around, making it less enjoyable to use.

As for functionality, it’s decent but not exceptional. The six buttons include a disproportionately large DPI button, and Mac users will find the thumb buttons unusable.

On the positive side, setting it up is easy, thanks to the external USB dongle. However, this alone doesn’t justify its high ratings.

Overall, while the Lekvey Ergonomic Mouse has merits, it falls short in comfort and usability compared to other options on the market.

Adesso iMouse E30

The Adesso iMouse E30 presents a myriad of usability issues. Its design seems to prioritize aesthetics over functionality, with a glossy finish that quickly becomes greasy and unpleasant to handle. The lack of clarity regarding the hand angle adds to the discomfort, potentially causing strain during extended use.

Despite its standard array of features like a scroll wheel and DPI button, the mouse’s overall build quality is subpar. The buttons feel flimsy, exacerbating the frustration of handling them. Additionally, relying on two AAA batteries might not be ideal for those looking for a more sustainable or convenient power source.

Furthermore, the language barrier with the accompanying software adds another layer of inconvenience, making customization and optimization inaccessible to many users. Considering these drawbacks, it’s evident that the Adesso iMouse E30 fails to justify its price tag and should be avoided at all costs.

Perixx PERIMICE-819B Bluetooth Portable Vertical Mouse

Perixx PERIMICE-819B Bluetooth Portable Vertical Mouse is a perfect compact companion for productivity on the move. Despite being one of the smaller mice in our tests, it packs a punch with its ergonomic design and convenient features. The 45-degree hand angle balances comfort and usability, ensuring a natural grip that minimizes strain during prolonged use. Paired with its soft rubber finish, it offers a secure hold, giving you confidence and control whether you’re tackling work tasks or gaming on the fly.

Designed for portability, the Perixx PERIMICE-819B Bluetooth Portable Vertical Mouse is tailor-made for professionals who are always on the move. Its small form factor makes it a breeze to slip into your laptop bag, ensuring that ergonomic support is always within reach, no matter where your adventures take you. The built-in 300 mAh battery provides long-lasting power, sparing you the hassle of frequent recharges and keeping you focused on what matters most.

In the performance department, it also doesn’t disappoint. With three DPI settings ranging from 1000 to 2400, it offers versatility to suit your specific needs and preferences. The soft-click main buttons deliver a satisfying tactile response, enhancing your overall user experience and making every click count. While the thumb buttons may not work natively on Mac OS, this minor drawback doesn’t detract from the status as a top contender in compact, ergonomic mice.

Lenovo Go

 Lenovo Go Wireless Vertical Mouse ReviewThe Lenovo Ergonomic Mouse boasts a sleek cork finish that instantly earns it the title of one of the coolest-looking mice in our test. What sets it apart from the rest is its unique 45-degree hand angle, promising a surprisingly comfortable grip that feels refreshingly natural. While it may require a bit more grip pressure due to its slimmer profile, this characteristic oddly adds to its overall appeal. Equipped with the standard buttons – two main buttons, a scroll wheel, a DPI selection button, and two thumb buttons – Lenovo ensures functionality without overwhelming the user. However, accessing the thumb buttons may initially feel a tad awkward, given their slightly higher positioning compared to conventional vertical ergonomic mice.

Lenovo doesn’t just focus on aesthetics and comfort; it also offers top-notch performance. With a DPI range from 800 to 2400, it stands out as one of the more sensitive mice in our tests, promising a dynamic user experience for those who demand precision. What distinguishes Lenovo is its innovative storage solution for battery and USB receivers. Unlike most mice that stash these components at the bottom, Lenovo opts for a top-mounted approach, ensuring easy access and efficient use of space.

Despite its merits, Lenovo isn’t without its minor flaws. While its finish may occasionally slip during adjustments, it remains a solid choice for those searching for a blend of style and functionality in their ergonomic mouse. Whether you prioritize aesthetics, comfort, or performance, Lenovo manages to deliver on all fronts, making it a compelling option

So this is our Top 5 Vertical Ergonomic Mouse!  Have any questions? Leave them below! Definitely SUBSCRIBE to our YouTube Channel to stay on top of all the new things we are reviewing!

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